Eastern Conference
| Rank | Teams | Played | Won | Drawn | Lost | Differential | Goal difference | Points | Current form |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
 Philadelphia Union |
17 | 10 | 4 | 3 | 32 - 18 | 14 | 34 | WWDWD |
| 2 |
 Inter Miami |
17 | 9 | 5 | 3 | 38 - 27 | 11 | 32 | LDWWW |
| 3 |
 Cincinnati |
17 | 9 | 3 | 5 | 25 - 24 | 1 | 30 | WDLDL |
| 4 |
 Nashville |
17 | 8 | 5 | 4 | 30 - 21 | 9 | 29 | WDWDD |
| 5 |
 Columbus Crew |
17 | 7 | 7 | 3 | 27 - 24 | 3 | 28 | DDLDL |
| 6 |
 Orlando City |
17 | 7 | 6 | 4 | 31 - 22 | 9 | 27 | WWWLL |
| 7 |
 New York RB |
17 | 8 | 3 | 6 | 28 - 19 | 9 | 27 | LLWWW |
| 8 |
 Chicago Fire |
16 | 7 | 4 | 5 | 35 - 29 | 6 | 25 | WWLWW |
| 9 |
 Charlotte |
17 | 8 | 1 | 8 | 28 - 27 | 1 | 25 | LLWLW |
| 10 |
 New York City |
17 | 7 | 4 | 6 | 20 - 20 | 0 | 25 | DWWLD |
| 11 |
 New England Revolution |
15 | 6 | 5 | 4 | 19 - 14 | 5 | 23 | DDDDW |
| 12 |
 DC United |
18 | 4 | 6 | 8 | 17 - 36 | -19 | 18 | DLDWL |
| 13 |
 Atlanta United |
18 | 4 | 5 | 9 | 21 - 32 | -11 | 17 | LWWLL |
| 14 |
 Toronto |
17 | 3 | 4 | 10 | 18 - 24 | -6 | 13 | LWLLL |
| 15 |
 Montréal |
17 | 1 | 5 | 11 | 12 - 32 | -20 | 8 | DLDLL |
Western Conference
| Rank | Teams | Played | Won | Drawn | Lost | Differential | Goal difference | Points | Current form |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
 Vancouver Whitecaps |
16 | 10 | 5 | 1 | 30 - 12 | 18 | 35 | DDWDW |
| 2 |
 San Diego |
17 | 9 | 3 | 5 | 29 - 18 | 11 | 30 | WDWLW |
| 3 |
 Minnesota United |
17 | 8 | 6 | 3 | 26 - 16 | 10 | 30 | LWDDW |
| 4 |
 Portland Timbers |
17 | 8 | 5 | 4 | 27 - 23 | 4 | 29 | DDLWW |
| 5 |
 Los Angeles |
16 | 7 | 5 | 4 | 30 - 23 | 7 | 26 | DWDDW |
| 6 |
 Seattle Sounders |
18 | 7 | 5 | 6 | 25 - 25 | 0 | 26 | DWWLL |
| 7 |
 Austin |
18 | 6 | 5 | 7 | 13 - 20 | -7 | 23 | DDDLW |
| 8 |
 San Jose Earthquakes |
17 | 6 | 4 | 7 | 34 - 28 | 6 | 22 | DDDWL |
| 9 |
 Colorado Rapids |
17 | 6 | 4 | 7 | 18 - 24 | -6 | 22 | LWWLL |
| 10 |
 Houston Dynamo |
17 | 5 | 5 | 7 | 22 - 25 | -3 | 20 | WWDWL |
| 11 |
 Dallas |
16 | 4 | 6 | 6 | 18 - 26 | -8 | 18 | DLLDD |
| 12 |
 Sporting Kansas City |
17 | 4 | 4 | 9 | 26 - 31 | -5 | 16 | DDDWL |
| 13 |
 Real Salt Lake |
17 | 4 | 3 | 10 | 16 - 25 | -9 | 15 | DLLDL |
| 14 |
 St. Louis City |
17 | 3 | 5 | 9 | 14 - 23 | -9 | 14 | DLLWL |
| 15 |
 LA Galaxy |
17 | 1 | 4 | 12 | 15 - 36 | -21 | 7 | LDLLW |
Qualification for round one and the CONCACAF Champions Cup round one
Qualification for Round One
Qualification for the Wild card round